TY  - JOUR
PY  - 2014//
TI  - Relationship between lifetime suicide attempts and schizotypal traits in patients with schizophrenia
JO  - PLoS one
A1  - Teraishi, Toshiya
A1  - Hori, Hiroaki
A1  - Sasayama, Daimei
A1  - Matsuo, Junko
A1  - Ogawa, Shintaro
A1  - Ishida, Ikki
A1  - Nagashima, Anna
A1  - Kinoshita, Yukiko
A1  - Ota, Miho
A1  - Hattori, Kotaro
A1  - Kunugi, Hiroshi
SP  - e107739
EP  - e107739
VL  - 9
IS  - 9
N2  - Patients with schizophrenia are at increased risk for suicide. Various risk factors for suicide have been reported in schizophrenia; however, few studies have examined the association between personality traits and suicidal behavior. We administered the Schizotypal Personality Questionnaire (SPQ) to 87 Japanese patients with schizophrenia (49 males; mean age 38.1±10.6 years) with and without a history of suicide attempts (SA and nSA groups, respectively), and 322 controls (158 males; mean age 40.8±13.9 years). As expected, an analysis of covariance (ANCOVA) controlling for age and sex showed that all SPQ indices (total SPQ score and all three factors, i.e., cognitive-perceptual, interpersonal, and disorganized) were significantly higher in patients with schizophrenia (SA+nSA groups), than controls (p<0.001 for all comparisons). Furthermore, there were significant differences in the total score and the interpersonal and disorganized factors between the SA and nSA groups (nSA<SA, p<0.01 for all comparisons). Receiver operating characteristic analysis showed that a total SPQ score of 33.5 was the optimal cut-off value to discriminate the SA group from the nSA group (χ2[1] = 10.6, p = 0.002, odds ratio: 4.7, 95% confidence interval: 1.8-12.1, sensitivity: 0.70, specificity: 0.67). These results suggest that high schizotypy is associated with lifetime suicide attempts, and that the total SPQ score might be useful to assess the risk of suicide attempt in patients with schizophrenia.<p />  <p>Language: en</p>
LA  - en
SN  - 1932-6203
UR  - http://dx.doi.org/10.1371/journal.pone.0107739
ID  - ref1
ER  -