TY  - JOUR
PY  - 1989//
TI  - The influence of age-dependent pharmacokinetics on the pharmacodynamics of hypnotic drugs: comparison of two hypnotics with different half-lives
JO  - International psychogeriatrics / IPA
A1  - Bergener, M.
A1  - Gola, R.
A1  - Hesse, C.
SP  - 17
EP  - 29
VL  - 1
IS  - 1
N2  - Drugs with a short elimination half-life should display fewer side effects than longer acting drugs in the treatment of sleep disturbances due to their smaller tendency to accumulate, especially in the elderly. This hypothesis could be confirmed in a double blind study of zopiclone versus flurazepam.<p /> <p>Language: en</p>
LA  - en
SN  - 1041-6102
UR  - http://dx.doi.org/
ID  - ref1
ER  -