TY  - JOUR
PY  - 1989//
TI  - Clinical application of a new enzyme-linked assay for the estimation of brain-specific creatine kinase in head injured patients
JO  - British journal of neurosurgery
A1  - Curley, P.
A1  - Abbott, R.
A1  - Vallance, D.
SP  - 655
EP  - 658
VL  - 3
IS  - 6
N2  - The clinical value of serum brain specific creatine kinase (CK-BB) was assessed in head injured patients (group A) using a new enzyme-linked immunosorbent assay (ELISA). The results were compared to healthy controls (group B) and patients post-myocardial infarction (group C). None of the head injured patients had undergone a surgical procedure or ventricular puncture. CK-BB was significantly higher in group A than in controls. The level of CK-BB in group A was inversely proportional to the Glasgow Coma Scale on admission. All patients with a CK-BB greater than 100 micrograms/l died. The ELISA technique is a simple and reliable assay with prognostic significance in patients with head injury and has wider clinical application than the previously described radioimmunoassay methods.<p /> <p>Language: en</p>
LA  - en
SN  - 0268-8697
UR  - http://dx.doi.org/
ID  - ref1
ER  -