TY  - JOUR
PY  - 2014//
TI  - Craniocerebral injury promotes the repair of peripheral nerve injury
JO  - Neural regeneration research
A1  - Wang, Weixu
A1  - Gao, Jun
A1  - Na, Lei
A1  - Jiang, Hongtao
A1  - Xue, Jingfeng
A1  - Yang, Zhenjun
A1  - Wang, Pei
SP  - 1703
EP  - 1708
VL  - 9
IS  - 18
N2  - The increase in neurotrophic factors after craniocerebral injury has been shown to promote fracture healing. Moreover, neurotrophic factors play a key role in the regeneration and repair of peripheral nerve. However, whether craniocerebral injury alters the repair of peripheral nerve injuries remains poorly understood. Rat injury models were established by transecting the left sciatic nerve and using a free-fall device to induce craniocerebral injury. Compared with sciatic nerve injury alone after 6-12 weeks, rats with combined sciatic and craniocerebral injuries showed decreased sciatic functional index, increased recovery of gastrocnemius muscle wet weight, recovery of sciatic nerve ganglia and corresponding spinal cord segment neuron morphologies, and increased numbers of horseradish peroxidase-labeled cells. These results indicate that craniocerebral injury promotes the repair of peripheral nerve injury.<p />  <p>Language: en</p>
LA  - en
SN  - 1673-5374
UR  - http://dx.doi.org/10.4103/1673-5374.141807
ID  - ref1
ER  -