TY  - JOUR
PY  - 2014//
TI  - Adversity in early and mid-adolescence is associated with elevated startle responses to safety cues in late adolescence
JO  - Clinical psychological science
A1  - Wolitzky-Taylor, Kate
A1  - Vrshek-Schallhorn, Suzanne
A1  - Waters, Allison M.
A1  - Mineka, Susan
A1  - Zinbarg, Rick
A1  - Ornitz, Edward
A1  - Naliboff, Bruce
A1  - Craske, Michelle G.
SP  - 202
EP  - 213
VL  - 2
IS  - 2
N2  - Elevated responding to safety cues in the context of threat is associated with anxiety disorder onset, but pathways underlying such responding remain unclear. This study examined whether childhood/adolescent adversity was associated with larger startle reflexes during safe phases of a fear potentiation startle paradigm (following delivery of an aversive stimulus) that predict anxiety disorders. Participants (N = 104) came from the Youth Emotion Project, a longitudinal study of risk factors for emotional disorders. Participants with no baseline psychopathology underwent a startle modulation protocol and were assessed for childhood and adolescent adversities using a validated interview. Adolescent adversity was associated with larger startle reflexes during the safe phases following an aversive stimulus. Neither child nor adolescent adversities were associated with responding during any other phase of the protocol. These findings suggest a pathway between adolescent adversity and a risk factor for anxiety disorders wherein adolescent adversity contributes to impaired responding to safety cues.<p />  <p>Language: en</p>
LA  - en
SN  - 2167-7026
UR  - http://dx.doi.org/10.1177/2167702613495840
ID  - ref1
ER  -