TY  - JOUR
PY  - 2014//
TI  - Alterations in circadian/seasonal rhythms and vegetative functions are related to suicidality in DSM-5 PTSD
JO  - BMC psychiatry
A1  - Dell Osso, Liliana
A1  - Massimetti, Gabriele
A1  - Conversano, Ciro
A1  - Bertelloni, Carlo
A1  - Carta, Mauro Giovanni
A1  - Ricca, Valdo
A1  - Carmassi, Claudia
SP  - 352
EP  - 352
VL  - 14
IS  - 1
N2  - Background: Alterations in rhythmicity and vegetative functions have been reported as correlates of suicidality, particularly in patients with mood disorders. No investigation has addressed their impact on patients with post-traumatic stress disorder (PTSD). Aim of the present study was to fulfill this gap.<br><br>METHODS: Sixty-five out- and inpatients with DSM-5 PTSD were assessed by using the Mood Spectrum-Self Report-Lifetime Version (MOODS-SR), a questionnaire for lifetime mood spectrum symptomatology including alterations in circadian/seasonal rhythms and vegetative functions. Six items of the MOODS-SR were combined and dichotomized to assess suicidal ideation and/or attempts.<br><br>RESULTS: Significant and positive associations were found between symptoms of lifetime dysregulations in rhythmicity and vegetative functions and suicidal ideation and/or attempts. All MOODS-SR sub-domains (rhythmicity, sleep, appetite/weight, sexual function, physical symptoms) were associated with an increased likelihood of suicidal ideation, but only changes in appetite/weight were associated with greater odd ratios of suicide attempts (OR = 2.099 95% CI 1.148-3.841).<br><br>CONCLUSIONS: Our results suggest that lifetime dysregulations in rhythmicity and vegetative functions may represent correlates of suicidality in patients with DSM-5 PTSD.<p />  <p>Language: en</p>
LA  - en
SN  - 1471-244X
UR  - http://dx.doi.org/10.1186/s12888-014-0352-2
ID  - ref1
ER  -