TY  - JOUR
PY  - 2001//
TI  - Correlation between serum IL-6 levels and death: usefulness in diagnosis of "traumatic shock"?
JO  - Tohoku journal of experimental medicine
A1  - Mimasaka, S.
A1  - Hashiyada, M.
A1  - Nata, M.
A1  - Funayama, M.
SP  - 319
EP  - 324
VL  - 193
IS  - 4
N2  - Interleukin-6 (IL-6) has been considered as an important mediator of inflammation. Clinically it is a well-known marker of the severity of injury following major trauma. In this study, the levels of IL-6 in body serum were applied to a traumatic death index. Of ninety victims 55 were men and 35 women, with a mean age of 53.4+/- 19 (S.D.) years. The cases were classified as traumatic deaths (38 cases), non-traumatic deaths other than natural causes of deaths (36 cases), and deaths due to natural causes (16 cases). All samples were collected within 2 days after death. The mean values of IL-6 levels of the traumatic, non-traumatic and disease groups were 8608.97, 2205.65, and 3266.64 pg/ml, respectively. Some cases in non-traumatic and disease cases were beyond 10 000 pg/ml, however, the mean value of the traumatic group was statistically higher than that of the other two groups. Even though several cases had high levels of IL-6 in spite of instantaneous death, the results showed that IL-6 levels are helpful in the diagnosis of traumatic shock.<p /> <p>Language: en</p>
LA  - en
SN  - 0040-8727
UR  - http://dx.doi.org/
ID  - ref1
ER  -