Aging is a multifactorial process that is associated with a progressive decline of multiple organ systems, leading to chronic disease, disability, and eventually death. The universal dream of humans is to live as long and healthy as possible. However, aging mechanism(s) are not clearly understood, making it difficult to develop anti-aging interventions. Several theories have been proposed to explain the inevitability of aging such as DNA damage, protein aggregation and misfolding, alteration in Ca++ signaling, accumulation of oxidative stress, apoptosis, and alteration in mitochondrial permeability.1 All these mechanisms have been targeted for designing anti-aging interventions. This CAM Corner will briefly review some proposed anti-aging interventions including calorie restriction, drugs, antioxidant supplements, specific foods, and vitamins.
Language: en
LA - en SN - 0884-5336 UR - http://dx.doi.org/10.1177/0884533614546889 ID - ref1 ER -