TY  - JOUR
PY  - 2015//
TI  - Developmental progression to early adult binge drinking and marijuana use from worsening versus stable trajectories of adolescent ADHD and delinquency
JO  - Addiction
A1  - Howard, Andrea L.
A1  - Molina, Brooke S. G.
A1  - Swanson, James M.
A1  - Hinshaw, Stephen P.
A1  - Belendiuk, Katherine A.
A1  - Harty, Seth C.
A1  - Arnold, L. Eugene
A1  - Abikoff, Howard B.
A1  - Hechtman, Lily
A1  - Stehli, Annamarie
A1  - Greenhill, Laurence L.
A1  - Newcorn, Jeffrey H.
A1  - Wigal, Timothy
SP  - 784
EP  - 795
VL  - 110
IS  - 5
N2  - AIMS: To examine the association between developmental trajectories of inattention, hyperactivity-impulsivity, and delinquency through childhood and adolescence (ages 8-16) and subsequent binge drinking and marijuana use in early adulthood (age 21). <br><br>DESIGN: Prospective naturalistic follow-up of children with attention-deficit/hyperactivity disorder (ADHD) previously enrolled in a randomized controlled trial (RCT). Treatment-phase assessments occurred at 3, 9, and 14 months after randomization; follow-up assessments occurred at 24 months, 36 months, and 6, 8, and 12 years after randomization. SETTING: Secondary analysis of data from the Multimodal Treatment Study of ADHD (MTA), a multi-site RCT comparing the effects of careful medication management, intensive behavior therapy, their combination, and referral to usual community care. PARTICIPANTS: 579 children with DSM-IV ADHD combined type, aged 7.0 and 9.9 years old at baseline (M=8.5, SD=.80). MEASUREMENTS: Ratings of inattention, hyperactivity-impulsivity, and delinquency were collected from multiple informants at baseline and through the 8-year follow-up. Self-reports of binge drinking and marijuana use were collected at the 12-year follow-up (M age 21). <br><br>FINDINGS: Trajectories of worsening inattention symptoms and delinquency (and less apparent improvement in hyperactivity-impulsivity) were associated with higher rates of early adult binge drinking and marijuana use, compared with trajectories of stable or improving symptoms and delinquency (of 24 comparisons, 22 p-values <.05), even when symptom levels in stable trajectories were high. <br><br>CONCLUSIONS: Worsening inattention symptoms and delinquency during adolescence are associated with increased levels of early adult substance use; this pattern may reflect a developmental course of vulnerability to elevated substance use in early adulthood.<p />  <p>Language: en</p>
LA  - en
SN  - 0965-2140
UR  - http://dx.doi.org/10.1111/add.12880
ID  - ref1
ER  -