TY - JOUR PY - 2015// TI - Reversible Splenial Lesion Syndrome (RESLES) following glufosinate ammonium poisoning JO - Journal of neuroimaging A1 - Jeong, Tae Oh A1 - Yoon, Jae Chol A1 - Lee, Jae Baek A1 - Jin, Young Ho A1 - Hwang, Seung Bae SP - 1050 EP - 1052 VL - 25 IS - 6 N2 - Isolated and reversible lesion restricted to the splenium of the corpus callosum, known as reversible splenial lesion syndrome, have been reported in patients with infection, high-altitude cerebral edema, seizures, antiepileptic drug withdrawal, or metabolic disturbances. Here, we report a 39-year-old female patient with glufosinate ammonium (GLA) poisoning who presented with confusion and amnesia. Diffusion-weighted magnetic resonance imaging of the brain revealed cytotoxic edema of the splenium of the corpus callosum. The lesion was not present on follow-up MR imaging performed 9 months later. We postulate that a GLA-induced excitotoxic mechanism was the cause of this reversible splenial lesion.

Language: en

LA - en SN - 1051-2284 UR - http://dx.doi.org/10.1111/jon.12216 ID - ref1 ER -