TY  - JOUR
PY  - 2015//
TI  - Association between adverse childhood experiences in the home and pediatric asthma
JO  - Annals of allergy, asthma and immunology
A1  - Wing, Robyn
A1  - Gjelsvik, Annie
A1  - Nocera, Mariann
A1  - McQuaid, Elizabeth L.
SP  - 379
EP  - 384
VL  - 114
IS  - 5
N2  - BACKGROUND: Numerous studies suggest that psychosocial factors could contribute to pediatric asthma. <br><br>OBJECTIVE: To examine the relation between single and cumulative adverse childhood experiences (ACEs), a measurement of household dysfunction, on parent report of lifetime asthma in children. <br><br>METHODS: This cross-sectional study used data from the 2011 to 2012 National Survey of Children's Health, a nationally representative sample of children 0 to 17 years old (n = 92,472). The main exposure was parent or guardian report of 6 ACE exposures (eg, witnessing domestic violence). The relation between ACE exposures and parent-reported diagnosis of childhood asthma was examined using multivariable logistic regression after controlling for demographic, socioeconomic, and behavioral covariates. <br><br>RESULTS: Overall asthma prevalence was 14.6%. Exposure prevalence to any ACE was 29.2%. Increased number of ACE exposures was associated with increased odds of asthma. In the adjusted model, the odds of reporting asthma were 1.28 (95% confidence interval [CI] 1.14-1.43) for those reporting 1 ACE, 1.73 (95% CI 1.27-2.36) for those with 4 ACEs, and 1.61 (95% CI 1.15-2.26) for those with 5 or 6 ACEs compared with those with no ACE exposures. Effects were moderated by Hispanic ethnicity. Hispanic children exposed to 4 ACEs had a 4.46 times increase in lifetime asthma (95% CI 2.46-8.08); white children had a 1.19 times increase (95% CI 0.80-1.79) compared with those exposed to 0 ACE. <br><br>CONCLUSION: This study supports the growing evidence for the biopsychosocial model of asthma onset. Future studies should examine the association between ACEs and specific asthma-related health outcomes.<p />  <p>Language: en</p>
LA  - en
SN  - 1081-1206
UR  - http://dx.doi.org/10.1016/j.anai.2015.02.019
ID  - ref1
ER  -