TY  - JOUR
PY  - 2015//
TI  - Areas of brain damage underlying increased reports of behavioral disinhibition
JO  - Journal of neuropsychiatry and clinical neurosciences
A1  - Knutson, Kristine M.
A1  - Dal Monte, Olga
A1  - Schintu, Selene
A1  - Wassermann, Eric M.
A1  - Raymont, Vanessa
A1  - Grafman, Jordan
A1  - Krueger, Frank
SP  - 193
EP  - 198
VL  - 27
IS  - 3
N2  - Disinhibition, the inability to inhibit inappropriate behavior, is seen in frontal-temporal degeneration, Alzheimer's disease, and stroke. Behavioral disinhibition leads to social and emotional impairments, including impulsive behavior and disregard for social conventions. The authors investigated the effects of lesions on behavioral disinhibition measured by the Neuropsychiatric Inventory in 177 veterans with traumatic brain injuries. The authors performed voxel-based lesion-symptom mapping using MEDx. Damage in the frontal and temporal lobes, gyrus rectus, and insula was associated with greater behavioral disinhibition, providing further evidence of the frontal lobe's involvement in behavioral inhibition and suggesting that these regions are necessary to inhibit improper behavior.<p />  <p>Language: en</p>
LA  - en
SN  - 0895-0172
UR  - http://dx.doi.org/10.1176/appi.neuropsych.14060126
ID  - ref1
ER  -