TY  - JOUR
PY  - 2015//
TI  - Cortical reorganization in an astronaut's brain after long-duration spaceflight
JO  - Brain structure and function
A1  - Demertzi, Athena
A1  - Van Ombergen, Angelique
A1  - Tomilovskaya, Elena
A1  - Jeurissen, Ben
A1  - Pechenkova, Ekaterina
A1  - Di Perri, Carol
A1  - Litvinova, Liudmila
A1  - Amico, Enrico
A1  - Rumshiskaya, Alena
A1  - Rukavishnikov, Ilya
A1  - Sijbers, Jan
A1  - Sinitsyn, Valentin
A1  - Kozlovskaya, Inessa B.
A1  - Sunaert, Stefan
A1  - Parizel, Paul M.
A1  - Van de Heyning, Paul H.
A1  - Laureys, Steven S. L.
A1  - Wuyts, Floris L.
SP  - 2873
EP  - 2876
VL  - 221
IS  - 5
N2  - To date, hampered physiological function after exposure to microgravity has been primarily attributed to deprived peripheral neuro-sensory systems. For the first time, this study elucidates alterations in human brain function after long-duration spaceflight. More specifically, we found significant differences in resting-state functional connectivity between motor cortex and cerebellum, as well as changes within the default mode network. In addition, the cosmonaut showed changes in the supplementary motor areas during a motor imagery task. These results highlight the underlying neural basis for the observed physiological deconditioning due to spaceflight and are relevant for future interplanetary missions and vestibular patients.<p />  <p>Language: en</p>
LA  - en
SN  - 1863-2653
UR  - http://dx.doi.org/10.1007/s00429-015-1054-3
ID  - ref1
ER  -