TY - JOUR PY - 2015// TI - Heroin crystal nephropathy JO - Clinical kidney journal A1 - Bautista, Josef Edrik Keith A1 - Merhi, Basma A1 - Gregory, Oliver A1 - Hu, Susie A1 - Henriksen, Kammi A1 - Gohh, Reginald SP - 339 EP - 342 VL - 8 IS - 3 N2 - In this paper we present an interesting case of acute kidney injury and severe metabolic alkalosis in a patient with a history of heavy heroin abuse. Urine microscopy showed numerous broomstick-like crystals. These crystals are also identified in light and electron microscopy. We hypothesize that heroin crystalizes in an alkaline pH, resulting in tubular obstruction and acute kidney injury. Management is mainly supportive as there is no known specific therapy for this condition. This paper highlights the utility of urine microscopy in diagnosing the etiology of acute kidney injury and proposes a novel disease called heroin crystal nephropathy.
Language: en
LA - en SN - 2048-8505 UR - http://dx.doi.org/10.1093/ckj/sfv018 ID - ref1 ER -