TY  - JOUR
PY  - 2015//
TI  - Plasma brain-derived neurotrophic factor levels in patients suffering from post-traumatic stress disorder
JO  - Psychiatry research
A1  - Su, Shanshan
A1  - Xiao, Zeping
A1  - Lin, Zhiguang
A1  - Qiu, Yongming
A1  - Jin, Yichao
A1  - Wang, Zhen
SP  - 365
EP  - 369
VL  - 229
IS  - 1-2
N2  - A number of studies have been done to investigate the role of brain-derived neurotrophic factor (BDNF) in patients with post-traumatic stress disorder (PTSD). In this study we aimed to test the relationship between plasma BDNF levels and PTSD. We solicited 65 subjects having recently experienced road traffic accidents (RTA) conforming to screening criteria. They were given follow-up examinations after one month, three months, and six months. PTSD was diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-R-TR, American Psychiatric Association, 2000) using the Mini International Neuropsychiatric Interview (MINI). All participants were divided into two groups: a group with PTSD and a group without PTSD. There were no significant differences in plasma BDNF levels between the two groups at either the 48h or six-month examination. Within the PTSD group, no significant differences were found in plasma BDNF levels between the two examinations. BDNF levels in those without PTSD showed a higher trend over time after trauma. Higher BDNF levels may be an important protective factor for the prevention of traumatized subjects from developing PTSD.<p />  <p>Language: en</p>
LA  - en
SN  - 0165-1781
UR  - http://dx.doi.org/10.1016/j.psychres.2015.06.038
ID  - ref1
ER  -