TY - JOUR PY - 2015// TI - Clinical variables associated with suicide attempts in schizophrenia before and after the first episode JO - Psychiatry research A1 - Togay, Bilge A1 - Noyan, Handan A1 - Tasdelen, Rumeysa A1 - Üçok, Alp SP - 252 EP - 256 VL - 229 IS - 1-2 N2 - The aim of this study was to investigate variables associated with suicide attempts in schizophrenia before and after the first episode. We evaluated history of past sucide attempts, clinical symptoms, level of functioning and cognitive performances of 172 patients with first-episode schizophrenia at first admission. Information was collected regarding clinical symptom severity, treatment compliance, and suicide attempts during the follow-up. We found that 16.5% of the patients attempted suicide before admission, and 6.2% of them attempted suicide during the follow-up. The patients who had attempted suicide before admission were mostly women, and more likely to be hospitalized in first year of follow up. BPRS-depression subscale score at admission and alcohol/substance use appeared as independent variables that found associated with suicide attempts prior to admission in logistic regression analysis. The patients who attempted suicide during the follow-up had significantly higher BPRS-depression subcale scores at sixth months of follow-up. Treatment compliance during the first 6 months and duration of remission was lower in this group. Our findings suggest that longer duration of first hospital treatment, the presence of depressive symptoms, and nonadherence to treatment in early phases of follow up after FES are predictors of suicide attempts. On the other hand, keeping remission during the follow-up protects against suicide attempts.

Language: en

LA - en SN - 0165-1781 UR - http://dx.doi.org/10.1016/j.psychres.2015.07.025 ID - ref1 ER -