TY  - JOUR
PY  - 2015//
TI  - Developmental outcomes of 3,4-methylenedioxymethamphetamine (ecstasy)-exposed infants in the UK
JO  - Human psychopharmacology
A1  - Singer, Lynn T.
A1  - Moore, Derek G.
A1  - Min, Meeyoung O.
A1  - Goodwin, Julia
A1  - Turner, John J. D.
A1  - Fulton, Sarah
A1  - Parrott, Andrew C.
SP  - 290
EP  - 294
VL  - 30
IS  - 4
N2  - OBJECTIVE: This paper aims to review findings from a longitudinal study of prenatal methylenedioxymethamphetamine (MDMA, "ecstasy") on infant development. <br><br>METHODS: In a prospective, longitudinal cohort design, we followed 28 MDMA-exposed and 68 non-MDMA-exposed infants from birth to 2 years of age. Women recruited voluntarily into a study of recreational drug use during pregnancy were interviewed to obtain type, frequency, and amount of recreational drug use. Their children were followed for a 2-year period after birth. A large number of drug and environmental covariates were controlled. Infants were seen at 1, 4, 12, 18, and 24 months using standardized normative tests of mental and motor development. <br><br>RESULTS: There were no differences between MDMA-exposed and non-MDMA-exposed infants at birth except that MDMA-exposed infants were more likely to be male. Motor delays were evident in MDMA infants at each age and amount of MDMA exposure predicted motor deficits at 12 months in a dose-dependent fashion. <br><br>CONCLUSIONS: Prenatal MDMA exposure is related to fine and gross motor delays in the first 2 years of life. Follow-up studies are needed to determine long-term effects. Copyright © 2015 John Wiley & Sons, Ltd.<p />  <p>Language: en</p>
LA  - en
SN  - 0885-6222
UR  - http://dx.doi.org/10.1002/hup.2459
ID  - ref1
ER  -