TY - JOUR PY - 2015// TI - Juvenile onset depression alters cardiac autonomic balance in response to psychological and physical challenges JO - Biological psychology A1 - Bylsma, Lauren M. A1 - Yaroslavsky, Ilya A1 - Rottenberg, Jonathan A1 - Jennings, J. Richard A1 - George, Charles J. A1 - Kiss, Eniko A1 - Kapornai, Krisztina A1 - Halas, Kitti A1 - Dochnal, Roberta A1 - Lefkovics, Eszter A1 - Benák, István A1 - Baji, Ildiko A1 - Vetró, Agnes A1 - Kovács, Mária SP - 167 EP - 174 VL - 110 IS - N2 - Cardiac autonomic balance (CAB) indexes the ratio of parasympathetic to sympathetic activation (Berntson et al., 2008), and is believed to reflect overall autonomic flexibility in the face of environmental challenges. However, CAB has not been examined in depression. We examined changes in CAB and other physiological variables in 179 youth with a history of juvenile onset depression (JOD) and 161 healthy controls, in response to two psychological (unsolvable puzzle, sad film) and two physical (handgrip, and forehead cold pressor) challenges. In repeated measures analyses, controls showed expected reductions in CAB for both the handgrip and unsolvable puzzle, reflecting a shift to sympathetic relative to parasympathetic activation. By contrast, JOD youth showed increased CAB from baseline for both tasks (ps<.05). No effects were found for the forehead cold pressor or sad film tasks, suggesting that CAB differences may arise under conditions requiring greater attentional control or sustained effort.

Language: en

LA - en SN - 0301-0511 UR - http://dx.doi.org/10.1016/j.biopsycho.2015.07.003 ID - ref1 ER -