TY  - JOUR
PY  - 2015//
TI  - Paraquat poisoning followed by toxic epidermal necrolysis: a report of two cases and published work review
JO  - Dermatology: international journal for clinical and investigative dermatology
A1  - Xu, Wei
A1  - Wang, Liya
A1  - Wang, Qiang
A1  - Li, Xin-Hua
A1  - Hu, Dayong
A1  - Li, Changbin
A1  - Wu, Tianfu
A1  - Mohan, Chandra
A1  - Peng, Ai
A1  - Shi, Yuling
SP  - 209
EP  - 212
VL  - 231
IS  - 3
N2  - Toxic epidermal necrolysis (TEN) is a life-threatening, typically drug-induced, mucocutaneous disease. Whether paraquat, one of the most widely used herbicides, could induce TEN is not known. We describe 2 paraquat-poisoned patients with TEN. Both patients presented erythema after hospital discharge following initial paraquat poisoning and then developed a widespread eruption of diffuse erythema on almost the whole body, with bullae, epidermal necrosis and sloughing. They were successfully treated with intravenous immunoglobulin and methylprednisolone. These clinical features were consistent with TEN caused by medications with a high risk to induce Stevens-Johnson syndrome/TEN. Moreover, it is suggested that both skin exposure and ingestion of paraquat could induce TEN. To our knowledge, this is the first case report of TEN related to paraquat poisoning. © 2015 S. Karger AG, Basel.<p />  <p>Language: en</p>
LA  - en
SN  - 1018-8665
UR  - http://dx.doi.org/10.1159/000433578
ID  - ref1
ER  -