TY  - JOUR
PY  - 2015//
TI  - Relationships of local lithium concentrations in drinking water to regional suicide rates in Italy
JO  - World journal of biological psychiatry
A1  - Pompili, Maurizio
A1  - Vichi, Monica
A1  - Dinelli, Enrico
A1  - Pycha, Roger
A1  - Valera, Paolo
A1  - Albanese, Stefano
A1  - Lima, Annamaria
A1  - De Vivo, Benedetto
A1  - Cicchella, Domenico
A1  - Fiorillo, Andrea
A1  - Amore, Mario
A1  - Girardi, Paolo
A1  - Baldessarini, Ross J.
SP  - 567
EP  - 574
VL  - 16
IS  - 8
N2  - OBJECTIVES: Higher natural concentrations of lithium in drinking water may be associated with lower local rates of suicide. <br><br>METHODS: Lithium concentrations in drinking water were assayed by mass spectrometry at 145 sites in Italy, and compared with reported local suicide rates for men and women between 1980 and 2011. <br><br>RESULTS: Lithium concentrations in drinking water averaged 5.28 [CI: 4.08-6.48] μg/L (0.761 [0.588-0.934] μEq/L) and ranged from 0.110 to 60.8 μg/L (1.58 to 8.76 μEq/L). Lithium concentrations and local suicide rates were not significantly inversely related, except in 1980-1989, particularly among women. <br><br>CONCLUSIONS: A proposed association between trace lithium concentrations in drinking water and risk of suicide was only partially supported, and mechanisms for potential clinical effects of trace levels of lithium are unknown.<p />  <p>Language: en</p>
LA  - en
SN  - 1562-2975
UR  - http://dx.doi.org/
ID  - ref1
ER  -