TY  - JOUR
PY  - 2015//
TI  - More than healthy bones: a review of vitamin D in muscle health
JO  - Therapeutic advances in musculoskeletal disease
A1  - Tanner, S. Bobo
A1  - Harwell, Susan A.
SP  - 152
EP  - 159
VL  - 7
IS  - 4
N2  - Vitamin D has known importance to bone health including calcium and phosphate homeostasis and appears to have a role in skeletal muscle health as well. Cases of vitamin D deficiency and insufficiency have been associated with poor muscle health. While the exact effects and mechanism of action remains controversial, current data lean towards insufficient vitamin D playing a role in musculoskeletal pain, sarcopenia, myopathy, falls and indirectly via cerebellar and cognitive dysfunction. Sophisticated experimental techniques have allowed detection of the vitamin D receptor (VDR) on skeletal muscle and cerebellar tissue, which if validated in further large studies, could confirm the mechanism of vitamin D in these associations. While further study is required, vitamin D repletion can have a substantial impact on muscle as well as bone health.<p />  <p>Language: en</p>
LA  - en
SN  - 1759-720X
UR  - http://dx.doi.org/10.1177/1759720X15588521
ID  - ref1
ER  -