TY  - JOUR
PY  - 2015//
TI  - Superwarfarine poisoning
JO  - Acta medica Portuguesa
A1  - Freixo, Ana
A1  - Lopes, Luís
A1  - Carvalho, Manuela
A1  - Araújo, Fernando
SP  - 389
EP  - 392
VL  - 28
IS  - 3
N2  - The superwarfarin-type anticoagulant rodenticides are used throughout the world and distinguish themselves from warfarin for its high potency and long acting anticoagulant activity. Easy access to these products enables the accidental or deliberate human poisoning. A case of voluntary rodenticide poisoning (RATIBRON®) by a woman who ingested an estimated 27.5 mg of bromadiolone total quantity for two weeks, with minor bleeding episodes, whose reversal of the anticoagulant effect with the correction of the abnormal values of the clotting tests took about one month to reverse is reported here. The correction of the haemostasis defects takes usually a long timeand there are no treatment guidelines, but a gradually vitamin K dosage reduction, as out patients, along with the monitoring of the International Normalized Ratio levels, allows a safe evaluation of the therapeutic response. <p />  <p>Language: pt</p>
LA  - pt
SN  - 0870-399X
UR  - http://dx.doi.org/
ID  - ref1
ER  -