TY - JOUR PY - 2015// TI - Today's threat of ricin toxin JO - Polski Merkuriusz Lekarski A1 - From, Sławomir A1 - Płusa, Tadeusz SP - 162 EP - 164 VL - 39 IS - 231 N2 - Since the late 70s of the last century there were more than 700 incidents related to the use of the ricin toxin. For this reason, CDC (Center of Disease Control and Prevention) recognized toxin as a biological weapon category B. The lethal dose of ricin toxin after parenteral administration is 0.0001 mg/kg and after oral administration 0.2 mg. The first symptoms of poisoning occur within a few hours after application of toxin as a nausea, vomiting and abdominal pain. In the final stage there are observed: cardiac arrhythmia, collapse and symptoms suggestive of involvement of the central nervous system. Stage immediately preceding death is a state of coma. The ricin toxin is still the substance against which action has no optimal antidote. Developed a vaccine called RiVax is waiting for its registration. It should be pointed out that the availability of a ricin toxin makes it possible to use it for real bioterrorists.

Language: pl

LA - pl SN - 1426-9686 UR - http://dx.doi.org/ ID - ref1 ER -