TY - JOUR PY - 2015// TI - Personality predictors of drinking outcomes in depressed alcohol-dependent patients JO - Alcohol and alcoholism A1 - Foulds, James A. A1 - Mulder, Roger T. A1 - Newton-Howes, Giles A1 - Adamson, Simon J. A1 - Boden, Joseph M. A1 - Sellman, J. Douglas SP - 296 EP - 301 VL - 51 IS - 3 N2 - AIM: To evaluate the role of personality dimensions as predictors of drinking outcomes in depressed alcohol-dependent patients.

METHODS: Temperament and character inventory (TCI) scores were obtained at baseline in a 24-week study of 127 depressed alcohol-dependent patients who received open-label naltrexone and were randomized to citalopram or placebo. The association between TCI personality dimensions and alcohol outcomes during follow-up was examined using general linear mixed models.

RESULTS: Low novelty seeking, high self-directedness and high cooperativeness predicted less alcohol consumption on drinking days during follow-up. Temperament and character variables had no effect on the percentage of days abstinent from alcohol. Depression mediated the effects of self-directedness and cooperativeness on alcohol outcomes while the effect of novelty seeking remained after adjusting for depression scores in follow-up.

CONCLUSION: Identifying personality characteristics at baseline predicts drinking outcomes in depressed, alcohol-dependent patients. In particular patients with high novelty seeking drank more heavily on drinking days and they may therefore need more intensive intervention to achieve good treatment outcomes.

Language: en

LA - en SN - 0735-0414 UR - http://dx.doi.org/10.1093/alcalc/agv122 ID - ref1 ER -