TY  - JOUR
PY  - 2015//
TI  - Incidence of suicide in patients with head and neck cancer
JO  - JAMA otolaryngology: head and neck surgery
A1  - Kam, David
A1  - Salib, Andrew
A1  - Gorgy, George
A1  - Patel, Tapan D.
A1  - Carniol, Eric T.
A1  - Eloy, Jean Anderson
A1  - Baredes, Soly
A1  - Park, Richard Chan Woo
SP  - 1075
EP  - 1081
VL  - 141
IS  - 12
N2  - IMPORTANCE: Suicide rates among patients with cancer in the US are significantly higher than those of the general population. To our knowledge, large cohort studies examining suicide rates among patients with head and neck cancer have not been performed. <br><br>OBJECTIVE: To identify incidence rate, trends, and risk factors of suicide in patients with cancer of the head and neck. DESIGN, SETTING, AND PARTICIPANTS: This was a retrospective cohort study of geographic areas served by the Surveillance, Epidemiology, and End Results (SEER) program. In total, 350 DESIGN, SETTING, AND PARTICIPANTS:  413 cases of patients with head and neck cancer were recorded within the SEER registry between 1973 and 2011. Data analyses were performed in 2014. Incidence data were calculated from the subset of that population that had the cause of death category coded as  DESIGN, SETTING, AND PARTICIPANTS: " DESIGN, SETTING, AND PARTICIPANTS: suicide and self-inflicted injury. DESIGN, SETTING, AND PARTICIPANTS: " EXPOSURES: Patients diagnosed as having a primary cancer of the head and neck region. MAIN OUTCOMES AND MEASURES: Influence of demographic factors, anatomic site of tumor, disease stage, and time since diagnosis on risk for suicide. <br><br>RESULTS: Among 350 RESULTS:  413 SEER registry patients with head and neck cancer, observed for 2 263 376 person-years, 857 suicides were identified with an age-, sex-, and race-adjusted suicide rate of 37.9/100 000 person-years. In contrast, the US general population suicide rate was 11.8 per 100 000 person-years. S RESULTS: uicide rates were higher in those treated with radiation alone (standardized mortality ratio [SMR], 5.12; 95% CI, 3.83-6.41) compared with those treated with surgery alone (SMR, 2.57; 95% CI, 1.66-3.49). The highest suicide risk was seen in patients with cancers of the hypopharynx (SMR, 13.91; 95% C RESULTS: I, 11.78-16.03) and larynx (SMR, 5.48; 95% CI, 4.14-6.81). <br><br>CONCLUSIONS AND RELEVANCE: Patients with head and neck cancer have more than 3 times the incidence of suicide compared with the general US population. Furthermore, suicide rates were highest among those with cancers of the larynx and hypopharynx.<p />  <p>Language: en</p>
LA  - en
SN  - 2168-6181
UR  - http://dx.doi.org/10.1001/jamaoto.2015.2480
ID  - ref1
ER  -