TY  - JOUR
PY  - 2015//
TI  - Exploring possible association between DβH genotype (C1021T), early onset of conduct disorder and psychopathic traits in juvenile delinquents
JO  - European archives of psychiatry and clinical neuroscience
A1  - Isaksson, Johan
A1  - Grigorenko, Elena L.
A1  - Oreland, Lars
A1  - af Klinteberg, Britt
A1  - Koposov, Roman A.
A1  - Ruchkin, Vladislav
SP  - 771
EP  - 773
VL  - 266
IS  - 8
N2  - Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.    Keywords: Juvenile justice .<p />  <p>Language: en</p>
LA  - en
SN  - 0940-1334
UR  - http://dx.doi.org/10.1007/s00406-015-0664-3
ID  - ref1
ER  -