TY  - JOUR
PY  - 2015//
TI  - Brain recovery after a plane crash: treatment with growth hormone (GH) and neurorehabilitation: a case report
JO  - International journal of molecular sciences
A1  - Devesa, Jesús
A1  - Díaz-Getino, Gustavo
A1  - Rey, Pablo
A1  - García-Cancela, José
A1  - Loures, Iria
A1  - Nogueiras, Sonia
A1  - Hurtado de Mendoza, Alba
A1  - Salgado, Lucía
A1  - González, Mónica
A1  - Pablos, Tamara
A1  - Devesa, Pablo
SP  - 30470
EP  - 30482
VL  - 16
IS  - 12
N2  - UNLABELLED: The aim of this study is to describe the results obtained after growth hormone (GH) treatment and neurorehabilitation in a young man that suffered a very grave traumatic brain injury (TBI) after a plane crash. <br><br>METHODS: Fifteen months after the accident, the patient was treated with GH, 1 mg/day, at three-month intervals, followed by one-month resting, together with daily neurorehabilitation. Blood analysis at admission showed that no pituitary deficits existed. At admission, the patient presented: spastic tetraplegia, dysarthria, dysphagia, very severe cognitive deficits and joint deformities. Computerized tomography scanners (CT-Scans) revealed the practical loss of the right brain hemisphere and important injuries in the left one. Clinical and blood analysis assessments were performed every three months for three years. Feet surgery was needed because of irreducible equinovarus. <br><br>RESULTS: Clinical and kinesitherapy assessments revealed a prompt improvement in cognitive functions, dysarthria and dysphagia disappeared and three years later the patient was able to live a practically normal life, walking alone and coming back to his studies. No adverse effects were observed during and after GH administration. <br><br>CONCLUSIONS: These results, together with previous results from our group, indicate that GH treatment is safe and effective for helping neurorehabilitation in TBI patients, once the acute phase is resolved, regardless of whether or not they have GH-deficiency (GHD).<p />  <p>Language: en</p>
LA  - en
SN  - 1661-6596
UR  - http://dx.doi.org/10.3390/ijms161226244
ID  - ref1
ER  -