TY  - JOUR
PY  - 1997//
TI  - Antisocial tendencies in alcohol-dependent men and their relation to harman, salsolinol and dopamine
JO  - Addiction biology
A1  - Podschus, J.
A1  - Dufeu, P.
A1  - Schmidt, L. G.
A1  - Sallstrom-Baum, S.
A1  - Rommelspacher, H.
SP  - 81
EP  - 86
VL  - 2
IS  - 1
N2  - Plasma dopamine, β-carbolines (norharman, harman) and isoquinolines ((R)- and (S)-salsolinol) were examined for their relationship to antisocial tendencies in 138 drinking men with an alcohol dependence syndrome according to ICD-10 criteria. Antisociality was assessed according to the following criteria: delinquency, involvement in fist-fights and homelessness. The personality structure was documented by the Tridimensional Personality Questionnaire of Cloninger. An early age of onset of alcohol dependence and a high degree of 'novelty seeking' were associated with antisocial tendencies. Of the β-carbolines and isoquinolines, harman and (S)-salsolinol were significantly decreased among antisocial alcoholics. Norharman, (R)-salsolinol and dopamine were not associated with antisocial personality. The contribution of endogenous alkaloids to the biological characterization of antisocial tendencies in alcoholics is described.<p /> <p>Language: en</p>
LA  - en
SN  - 1355-6215
UR  - http://dx.doi.org/10.1080/13556219772886
ID  - ref1
ER  -