TY - JOUR
PY - 2015//
TI - Measurement of intracranial pressure and short-term outcomes of patients with traumatic brain injury: a propensity-matched analysis
JO - Revista Brasileira de terapia intensiva
A1 - Ferreira, César Biselli
A1 - Bassi, Estevão
A1 - Lucena, Lucas
A1 - Carreta, Hernandez
A1 - Miranda, Leandro Costa
A1 - Tierno, Paulo Fernando Guimarães Mazorcchi
A1 - Amorim, Robson Luis
A1 - Zampieri, Fernando Godinho
A1 - Malbouisson, Luis Marcelo Sá
SP - 315
EP - 321
VL - 27
IS - 4
N2 - OBJECTIVE: To assess the impact of intracranial pressure monitoring on the short-term outcomes of traumatic brain injury patients.
METHODS: Retrospective observational study including 299 consecutive patients admitted due to traumatic brain injury from January 2011 through July 2012 at a Level 1 trauma center in São Paulo, Brazil. Patients were categorized in two groups according to the measurement of intracranial pressure (measured intracranial pressure and non-measured intracranial pressure groups). We applied a propensity-matched analysis to adjust for possible confounders (variables contained in the Crash Score prognostic algorithm).
RESULTS: Global mortality at 14 days (16%) was equal to that observed in high-income countries in the CRASH Study and was better than expected based on the CRASH calculator score (20.6%), with a standardized mortality ratio of 0.77. A total of 28 patients received intracranial pressure monitoring (measured intracranial pressure group), of whom 26 were paired in a 1:1 fashion with patients from the non-measured intracranial pressure group. There was no improvement in the measured intracranial pressure group compared to the non-measured intracranial pressure group regarding hospital mortality, 14-day mortality, or combined hospital and chronic care facility mortality. Survival up to 14 days was also similar between groups.
CONCLUSION: Patients receiving intracranial pressure monitoring tend to have more severe traumatic brain injuries. However, after adjusting for multiple confounders using propensity scoring, no benefits in terms of survival were observed among intracranial pressure-monitored patients and those managed with a systematic clinical protocol.
Language: pt
LA - pt SN - 0103-507X UR - http://dx.doi.org/10.5935/0103-507X.20150055 ID - ref1 ER -