TY - JOUR PY - 2016// TI - History of diabetes and risk of suicide and accidental death in Japan: the Japan Public Health Centre-based Prospective Study, 1990-2012 JO - Diabetes and metabolism A1 - Yamauchi, T. A1 - Inagaki, M. A1 - Yonemoto, N. A1 - Iwasaki, M. A1 - Akechi, T. A1 - Sawada, N. A1 - Iso, H. A1 - Noda, M. A1 - Tsugane, S. SP - 184 EP - 191 VL - 42 IS - 3 N2 - AIM: This study looked at whether a history of diabetes mellitus (DM) is associated with a higher risk of externally caused death (by suicide and accident), using data for a large population-based prospective cohort from an Asian population.

METHODS: Data collected between 1990 and 2012 from the Japan Public Health Centre-based Prospective Study were analyzed, and Poisson regression models were used to calculate adjusted risk ratios (RR) for external causes of death.

RESULTS: The population-based cohort comprised 105,408 Japanese residents (49,484 men and 55,924 women; mean age: 51.2 [SD 7.9] years). At baseline, 3250 (6.6%) men and 1648 (3.0%) women had a history of DM. During the follow-up period, 113 external deaths (41 suicides and 72 accidents) were noted among those with a history of DM, with 1304 external deaths (577 suicides and 727 accidents) among those without such a history. A higher risk of external death (men, RR: 1.4, 95% CI: 1.2-1.8; women, RR: 1.6, 95% CI: 1.01-2.4) was observed in those with a history of DM. Also, among those aged 40-49 years (RR: 1.9, 95% CI: 1.3-2.7) and 50-59 years (RR: 1.4, 95% CI: 1.05-1.9) at baseline, the risk of external death was significantly higher in those with a history of DM.

CONCLUSION: Compared with people with no history of DM, those with such a history had a significantly greater risk of externally caused death (particularly accidental deaths) in both genders and in those aged≤59 years at baseline.

Language: en

LA - en SN - 1262-3636 UR - http://dx.doi.org/10.1016/j.diabet.2015.11.008 ID - ref1 ER -