TY  - JOUR
PY  - 2016//
TI  - Drug-induced long QT syndrome increases the risk of drowning
JO  - Medical hypotheses
A1  - Vincenzi, Frank F.
SP  - 11
EP  - 13
VL  - 87
IS  - 
N2  - There is strong evidence linking inherited long QT syndromes with an increased risk of drowning due to fatal arrhythmias in the water. Drug-induced long QT syndrome (DILQTS) is hypothesized to increase the risk of drowning by similar mechanisms. It is suggested that QT prolongation caused by a drug or drugs, when combined with the autonomic conflict associated with the mammalian dive reflex and/or the cold shock reflex, sets up conditions that may result in a sudden fatal arrhythmia while in water - thus an increased risk of drowning related to a drug-induced prolongation of the QT interval. Many widely used drugs prolong the QT interval thus raising a drug safety issue that needs confirmation or refutation.<p />  <p>Language: en</p>
LA  - en
SN  - 0306-9877
UR  - http://dx.doi.org/10.1016/j.mehy.2015.12.015
ID  - ref1
ER  -