TY - JOUR PY - 2012// TI - Reduced N400 semantic priming effects in adult survivors of paediatric and adolescent traumatic brain injury JO - Brain and language A1 - Knuepffer, C. A1 - Murdoch, B. E. A1 - Lloyd, D. A1 - Lewis, F. M. A1 - Hinchliffe, F. J. SP - 52 EP - 63 VL - 123 IS - 1 N2 - The immediate and long-term neural correlates of linguistic processing deficits reported following paediatric and adolescent traumatic brain injury (TBI) are poorly understood. Therefore, the current research investigated event-related potentials (ERPs) elicited during a semantic picture-word priming experiment in two groups of highly functioning individuals matched for various demographic variables and behavioural language performance. Participants in the TBI group had a recorded history of paediatric or adolescent TBI involving injury mechanisms associated with diffuse white matter pathology, while participants in the control group never sustained any insult to the brain. A comparison of N400 Mean Amplitudes elicited during three experimental conditions with varying semantic relatedness between the prime and target stimuli (congruent, semantically related, unrelated) revealed a significantly smaller N400 response in the unrelated condition in the TBI group, indicating residual linguistic processing deviations when processing demands required the quick detection of a between-category (unrelated) violation of semantic expectancy. (Contains 2 tables and 4 figures.)

Language: en

LA - en SN - 0093-934X UR - http://dx.doi.org/10.1016/j.bandl.2012.06.009 ID - ref1 ER -