TY  - JOUR
PY  - 2016//
TI  - Suicide by self-injection of chlormequat trademark C5SUN(®)
JO  - Forensic science international
A1  - Boumrah, Yacine
A1  - Gicquel, Thomas
A1  - Hugbart, Chloé
A1  - Baert, Alain
A1  - Morel, Isabelle
A1  - Bouvet, Renaud
SP  - e9
EP  - e13
VL  - 263
IS  - 
N2  - Chlormequat is a quaternary ammonium used as plant growth regulating agent. We report here the first suicide case involving a 45 year-old farmer man who intentionally self-injected C5SUN(®), containing chlormequat and choline. An original liquid chromatography high resolution mass spectrometry method (LC-HR-MS), using a hybrid quadrupole-orbitrap mass spectrometer, was developed for qualitative and quantitative analysis of chlormequat in different biological matrices. Toxicological analyses of post-mortem samples highlighted the presence of chlormequat in the blood (2.25mg/L) and the urine (4.45mg/L), in addition to ethanol impregnation blood (1.15g/L). The route of administration (subcutaneous injection) was confirmed by the detection of chlormequat in the abdominal fat sample (chlormequat: 10.04mg/g) taken from the traumatic injury location, as well as in the syringe found at the death scene, close to the victim's body. Based on the results of these post-mortem investigations, the cause of death was determined to be consecutive to cardiac dysrhythmia and cardiac arrest following chlormequat self-injection.<br><br>Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0379-0738
UR  - http://dx.doi.org/10.1016/j.forsciint.2016.03.007
ID  - ref1
ER  -