TY - JOUR PY - 2016// TI - Homicidal poisoning in China using several anesthetic drugs JO - Journal of forensic sciences A1 - Ye, Yi A1 - Yan, Youyi A1 - Gong, Daoyin A1 - Guo, Run A1 - Yang, Lin A1 - Liao, Linchuan SP - 864 EP - 866 VL - 61 IS - 3 N2 - The authors describe a case of a well-designed homicidal poisoning in China. A male was treated with starvation, intravenous fluids and antibiotics while in the hospital for acute diarrhea. He suddenly suffered from shortness of breath and subsequently died. A forensic autopsy was carried out, and several specimens were collected for toxicological screening. Propofol was tentatively identified in the blood by GC-MS. Based on the presence of propofol in the blood, a suspect confessed that two other drugs, namely midazolam and vecuronium, were involved in this murder. Analytical drug quantification was then performed by GC-MS and LC-MS/MS. Blood analysis revealed the following: propofol at 0.5 μg/mL, midazolam at 0.098 μg/mL, and vecuronium at 0.10 μg/mL. These results suggest that the cause of death was respiratory depression due to the acute combined effect of several anesthetic drugs administered by the victim's companion.

© 2016 American Academy of Forensic Sciences.

Language: en

LA - en SN - 0022-1198 UR - http://dx.doi.org/10.1111/1556-4029.13035 ID - ref1 ER -