TY  - JOUR
PY  - 2016//
TI  - Post-traumatic stress disorder and opioid use disorder: a narrative review of conceptual models
JO  - Journal of addictive diseases
A1  - Danovitch, Itai
SP  - 169
EP  - 179
VL  - 35
IS  - 3
N2  - Post-traumatic stress disorder is highly prevalent among individuals who suffer from opioid use disorder. Compared to individuals with opioid use disorder alone, those with post-traumatic stress disorder have a worse course of illness, occupational functioning, and physical health. The neurobiological pathways underlying each disorder overlap substantially, and there are multiple pathways through which these disorders may interact. This narrative review explores evidence underpinning 3 explanatory perspectives on comorbid post-traumatic stress disorder and opioid use disorder: The opioid susceptibility model (a.k.a.: the Self-Medication Hypothesis), the post-traumatic stress disorder susceptibility model, and the common factors model. Diagnostic implications, treatment implications, and directions for future research are discussed.<p />  <p>Language: en</p>
LA  - en
SN  - 1055-0887
UR  - http://dx.doi.org/10.1080/10550887.2016.1168212
ID  - ref1
ER  -