TY  - JOUR
PY  - 2016//
TI  - Update on causes of premature death in people with convulsive epilepsy in rural West China
JO  - Epilepsia
A1  - Si, Yang
A1  - Chen, Deng
A1  - Tian, Linyu
A1  - Mu, Jie
A1  - Chen, Tao
A1  - Liu, Ling
A1  - Deng, Ying
A1  - He, Jun
A1  - Li, You
A1  - He, Li
A1  - Zhou, Dong
SP  - e117
EP  - 20
VL  - 57
IS  - 6
N2  - This longitudinal prospective study updated a previous report on premature mortality and focused on the risk factors among patients with convulsive epilepsy in resource-poor settings. The present cohort size (7,231) and follow-up (mean 33.4 months) were expanded. The basic epidemiologic aspects of this cohort were similar to the original report (case fatality: 3.26% vs. 2.97%, respectively; injury contributed more than half of the deaths). Cox regression analysis suggested that male patients, late ages of onset (>45 years old), short duration of epilepsy (<10 years), and high convulsive seizure frequency (>2 per month) were independent risk factors for overall premature death. Male patients with late ages of onset and high seizure frequency had a higher risk of injury-specific death. This study emphasizes the preventable nature of injuries that are leading putative causes of death among people with convulsive epilepsy in rural West China. Education on specific populations and efficient seizure control are of paramount importance in reducing the risk of premature mortality.<br><br>Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.<p />  <p>Language: en</p>
LA  - en
SN  - 0013-9580
UR  - http://dx.doi.org/10.1111/epi.13395
ID  - ref1
ER  -