TY - JOUR PY - 2016// TI - Amygdala volumetric change following psychotherapy for posttraumatic stress disorder JO - Journal of neuropsychiatry and clinical neurosciences A1 - Laugharne, Jonathan A1 - Kullack, Claire A1 - Lee, Christopher W. A1 - McGuire, Tracy A1 - Brockman, Simone A1 - Drummond, Peter D. A1 - Starkstein, Sergio SP - ePub EP - ePub VL - ePub IS - ePub N2 - The authors investigated the impact of eye movement desensitization and reprocessing (EMDR) and prolonged exposure (PE) on the volumes of the amygdala and hippocampus, structures known to be important in fear conditioning, in 20 patients with posttraumatic stress disorder (PTSD). Patients were randomly allocated to either EMDR or PE. Volumes were assessed before and after treatment via magnetic resonance imaging (MRI). Both groups showed significant improvements in PTSD symptoms. Left amygdala mean volume increased significantly following EMDR treatment only. No significant volumetric changes were found for the hippocampus.

Language: en

LA - en SN - 0895-0172 UR - http://dx.doi.org/10.1176/appi.neuropsych.16010006 ID - ref1 ER -