TY  - JOUR
PY  - 2016//
TI  - Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality
JO  - Addiction
A1  - Naimi, Timothy S.
A1  - Stockwell, Timothy
A1  - Zhao, Jinhui
A1  - Xuan, Ziming
A1  - Dangardt, Frida
A1  - Saitz, Rich
A1  - Liang, Wenbin
A1  - Chikritzhs, Tanya
SP  - 207
EP  - 214
VL  - 112
IS  - 2
N2  - Selection biases may lead to systematic overestimate of protective effects from 'moderate' alcohol consumption. Overall, most sources of selection bias favor low-volume drinkers Gaetanoers in relation to non-drinkers. Studies that attempt to address these types of bias generally find attenuated or non-significant relationships between low-volume alcohol consumption and cardiovascular disease, which is the major source of possible protective effects on mortality from low-volume consumption. Furthermore, observed mortality effects among established low-volume consumers are of limited relevance to health-related decisions about whether to initiate consumption or to continue drinking purposefully into old age. Short of randomized trials with mortality end-points, there are a number of approaches that can minimize selection bias involving low-volume alcohol consumption.<br><br>© 2016 Society for the Study of Addiction.<p />  <p>Language: en</p>
LA  - en
SN  - 0965-2140
UR  - http://dx.doi.org/10.1111/add.13451
ID  - ref1
ER  -