TY  - JOUR
PY  - 2016//
TI  - Flexible modulation of risk attitude during decision-making under quota
JO  - NeuroImage
A1  - Fujimoto, Atsushi
A1  - Takahashi, Hidehiko
SP  - 304
EP  - 312
VL  - 139
IS  - 
N2  - Risk attitude is often regarded as an intrinsic parameter in the individual personality. However, ethological studies reported state-dependent strategy optimization irrespective of individual preference. To synthesize the two contrasting literatures, we developed a novel gambling task that dynamically manipulated the quota severity (required outcome to clear the task) in a course of choice trials and conducted a task-fMRI study in human participants. The participants showed their individual risk preference when they had no quota constraint ('individual-preference mode'), while they adopted state-dependent optimal strategy when they needed to achieve a quota ('strategy-optimization mode'). fMRI analyses illustrated that the interplay among prefrontal areas and salience-network areas reflected the quota severity and the utilization of the optimal strategy, shedding light on the neural substrates of the quota-dependent risk attitude. Our results demonstrated the complex nature of risk-sensitive decision-making and may provide a new perspective for the understanding of problematic risky behaviors in human.<br><br>Copyright © 2016. Published by Elsevier Inc.<p />  <p>Language: en</p>
LA  - en
SN  - 1053-8119
UR  - http://dx.doi.org/10.1016/j.neuroimage.2016.06.040
ID  - ref1
ER  -