TY  - JOUR
PY  - 2016//
TI  - Canopy venom: proteomic comparison among new world arboreal pit-viper venoms
JO  - Toxins (Basel)
A1  - Debono, Jordan
A1  - Cochran, Chip
A1  - Kuruppu, Sanjaya
A1  - Nouwens, Amanda
A1  - Rajapakse, Niwanthi W.
A1  - Kawasaki, Minami
A1  - Wood, Kelly
A1  - Dobson, James
A1  - Baumann, Kate
A1  - Jouiaei, Mahdokht
A1  - Jackson, Timothy N. W.
A1  - Koludarov, Ivan
A1  - Low, Dolyce
A1  - Ali, Syed A.
A1  - Smith, A. Ian
A1  - Barnes, Andrew
A1  - Fry, Bryan G.
SP  - e8070210
EP  - e8070210
VL  - 8
IS  - 7
N2  - Central and South American pitvipers, belonging to the genera Bothrops and Bothriechis, have independently evolved arboreal tendencies. Little is known regarding the composition and activity of their venoms. In order to close this knowledge gap, venom proteomics and toxin activity of species of Bothriechis, and Bothrops (including Bothriopsis) were investigated through established analytical methods. A combination of proteomics and bioactivity techniques was used to demonstrate a similar diversification of venom composition between large and small species within Bothriechis and Bothriopsis. Increasing our understanding of the evolution of complex venom cocktails may facilitate future biodiscoveries.<p />  <p>Language: en</p>
LA  - en
SN  - 2072-6651
UR  - http://dx.doi.org/10.3390/toxins8070210
ID  - ref1
ER  -