TY  - JOUR
PY  - 2016//
TI  - (1)H-MRS and MEGA-PRESS pulse sequence in the study of balance of inhibitory and excitatory neurotransmitters in the human brain of ultra-high risk of schizophrenia patients
JO  - Doklady. biochemistry and biophysics
A1  - Menschikov, P. E.
A1  - Semenova, N. A.
A1  - Ublinskiy, M. V.
A1  - Akhadov, T. A.
A1  - Keshishyan, R. A.
A1  - Lebedeva, I. S.
A1  - Omelchenko, M. A.
A1  - Kaleda, V. G.
A1  - Varfolomeev, S. D.
SP  - 168
EP  - 172
VL  - 468
IS  - 1
N2  - The MEGA-PRESS pulse sequence was used for determination of overlapping signals in the (1)H-MRS spectra of the human brain. For the first time, the balance of GABA glutamate/glutamine concentrations was estimated quantitatively in the human brain of patients with ultra-high risk of schizophrenia. It was found that GABA concentration and GABA/GLX ratios were significantly reduced in the left frontal lobe of UHR subjects.<p />  <p>Language: en</p>
LA  - en
SN  - 1607-6729
UR  - http://dx.doi.org/10.1134/S1607672916030029
ID  - ref1
ER  -