TY - JOUR
PY - 2016//
TI - Reducing smoking reduces suicidality among individuals with psychosis: complementary outcomes from a Healthy Lifestyles intervention study
JO - Psychiatry research
A1 - Sankaranarayanan, Anoop
A1 - Clark, Vanessa
A1 - Baker, Amanda
A1 - Palazzi, Kerrin
A1 - Lewin, Terry J.
A1 - Richmond, Robyn
A1 - Kay-Lambkin, Frances J.
A1 - Filia, Sacha
A1 - Castle, David
A1 - Williams, Jill M.
SP - 407
EP - 412
VL - 243
IS -
N2 - This study sought to explore the impact of smoking reduction on suicidality (suicide ideation and behaviour) among people with a psychotic disorder (n=235) who participated in a randomized trial of a healthy lifestyle intervention trial. Suicidality, measured by item -4 of the Brief Psychiatric Rating Scale (BPRS) was the main variable of interest. Measures were collected by research assistants blind to treatment allocation at baseline, at 15 weeks (mid-intervention) and 12 months after baseline. Mediation analysis, adjusted for confounders, was used to determine the relationship between smoking reduction and suicidality and to explore whether this was mediated through depression. At 12 months, smoking reduction was found to be significantly associated with suicidality change; an association was also seen between smoking reduction and depression and depression and suicidality. After adjusting for depression, the association between smoking reduction and suicidality was attenuated but remained statistically significant; the proportion of the total effect that was mediated through depression was 30%. There was no significant association between suicidality and treatment group (vs. controls) over time. Our study suggests that smoking interventions may have benefits over and above those for improved physical health, by reducing suicidal ideation in people with psychosis.
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved. Language: en
LA - en
SN - 0165-1781
UR - http://dx.doi.org/10.1016/j.psychres.2016.07.006
ID - ref1
ER -