TY  - JOUR
PY  - 2016//
TI  - Risk factors for suicide among patients with schizophrenia: a cohort study focused on cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid
JO  - Neuropsychiatric disease and treatment
A1  - Neider, Daniel
A1  - Lindström, Leif H.
A1  - Bodén, Robert
SP  - 1711
EP  - 1714
VL  - 12
IS  - 
N2  - BACKGROUND: The objective of this study was to investigate the association between 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid (CSF), bullying, and later suicide among patients with schizophrenia. <br><br>METHODS: Ninety-nine patients with schizophrenia were included. Correlations of clinical factors, 5-HIAA and HVA, and later suicide were investigated. <br><br>RESULTS: Twelve patients committed suicide (12%) during a 28-year follow-up period. Later suicide was correlated to bullying in childhood (P=0.02) and a lower quotient of HVA/5-HIAA in CSF (P<0.05). <br><br>CONCLUSION: Suicide in schizophrenia is related to childhood exposedness and CSF neurotransmitter levels.<p />  <p>Language: en</p>
LA  - en
SN  - 1176-6328
UR  - http://dx.doi.org/10.2147/NDT.S107178
ID  - ref1
ER  -