TY  - JOUR
PY  - 2016//
TI  - Brain natriuretic peptide as a marker of severity of patient's condition after severe traumatic brain injury
JO  - Anesteziologiia i Reanimatologiia
A1  - Sychev, A. A.
A1  - Savin, I. A.
A1  - Goyachev, A. S.
A1  - Tenedieva, V. D.
A1  - Oshorov, A. V.
A1  - Polupan, A. A.
A1  - Gavrilov, A. G.
A1  - Potapov, A. A.
SP  - 108
EP  - 112
VL  - 61
IS  - 2
N2  - The aim of the study was to assess the significance of NT-proBNP levels as a predictor of the severity of patients' condition after severe TBI and critical stress of the heart. In this prospective observational study 118 patients admitted on 1-4 day after severe TBI (GCS <8 points on admission) was supervised. The average age of patients was 32 +/- 16 years, 28 women and 90 men were in this group. 12 of the observed patients died within the first 10 days. NT-proBNP level was determined by immunochemiluminescent analyzer "Immulite 2000" (Siemens). Blood sampling was performed daily at 8:00 am during the acute period--an average for 7 days (5 to 10) from the date of admission. At the same time hemodynamic status was assessed by PiCCO. It has been shown that NT-proBNP level may be not only a marker of severity of condition and poor outcome in patients with severe TBI, but also can be used as a good predictor of exhaustion of compensatory myocardial capacity in these patients.<p />  <p>Language: ru</p>
LA  - ru
SN  - 0201-7563
UR  - http://dx.doi.org/
ID  - ref1
ER  -