TY  - JOUR
PY  - 2016//
TI  - Clinical correlates of plasma brain-derived neurotrophic factor in post-traumatic stress disorder spectrum after a natural disaster
JO  - Psychiatry research
A1  - Stratta, Paolo
A1  - Sanità, Patrizia
A1  - Bonanni, Roberto L.
A1  - de Cataldo, Stefano
A1  - Angelucci, Adriano
A1  - Rossi, Rodolfo
A1  - Origlia, Nicola
A1  - Domenici, Luciano
A1  - Carmassi, Claudia
A1  - Piccinni, Armando
A1  - Dell'osso, Liliana
A1  - Rossi, Alessandro
SP  - 165
EP  - 170
VL  - 244
IS  - 
N2  - Clinical correlates of plasma Brain-Derived Neurotrophic Factor (BDNF) have been investigated in a clinical population with Post Traumatic Stress Disorder (PTSD) symptoms and healthy control subjects who survived to the L'Aquila 2009 earthquake. Twenty-six outpatients and 14 control subjects were recruited. Assessments included: Structured Clinical Interview for DSM-IV Axis-I disorders Patient Version, Trauma and Loss Spectrum-Self Report (TALS-SR) for post-traumatic spectrum symptoms. Thirteen patients were diagnosed as Full PTSD and 13 as Partial PTSD. The subjects with full-blown PTSD showed lower BDNF level than subjects with partial PTSD and controls. Different relationship patterns of BDNF with post-traumatic stress spectrum symptoms have been reported in the three samples. Our findings add more insight on the mechanisms regulating BDNF levels in response to stress and further proofs of the utility of the distinction of PTSD into full and partial categories.<br><br>Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0165-1781
UR  - http://dx.doi.org/10.1016/j.psychres.2016.07.019
ID  - ref1
ER  -