TY - JOUR PY - 2016// TI - Pathophysiology of hemorragic shock JO - Transfusion clinique et biologique A1 - Copotoiu, R. A1 - Cinca, E. A1 - Collange, O. A1 - Levy, F. A1 - Mertes, P-m SP - 222 EP - 228 VL - 23 IS - 4 N2 - This review addresses the pathophysiology of hemorrhagic shock, a condition produced by rapid and significant loss of intravascular volume, which may lead to hemodynamic instability, decreases in oxygen delivery, decreased tissue perfusion, cellular hypoxia, organ damage, and death. The initial neuroendocrine response is mainly a sympathetic activation. Haemorrhagic shock is associated altered microcirculatory permeability and visceral injury. It is also responsible for a complex inflammatory response associated with hemostasis alteration.

Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Language: fr

LA - fr SN - 1246-7820 UR - http://dx.doi.org/10.1016/j.tracli.2016.07.004 ID - ref1 ER -