TY - JOUR PY - 2016// TI - Heightened early-attentional stimulus orienting and impulsive action in men with antisocial personality disorder JO - European archives of psychiatry and clinical neuroscience A1 - Lijffijt, Marijn A1 - Lane, Scott D. A1 - Mathew, Sanjay J. A1 - Stanford, Matthew S. A1 - Swann, Alan C. SP - ePub EP - ePub VL - ePub IS - ePub N2 - We tested whether enhanced stimulus orienting operationalized as N1 and P2 auditory evoked potentials to increasing loudness (50-90 dB clicks) could be associated with trait impulsivity (Barratt Impulsiveness Scale, BIS-11), impulsive action (commission error on the Immediate Memory Task), or impulsive choice (immediate responses on temporal discounting tasks). We measured N1 and P2 loudness sensitivity in a passive listening task as linear intensity-sensitivity slopes in 36 men with antisocial personality disorder with a history of conviction for criminal conduct and 16 healthy control men. Across all subjects, regression analyses revealed that a steeper P2 slope predicted higher IMT commission error/correct detection ratio, and lower stimulus discriminability (A-prime). These associations were also found within both groups. These relationships suggest an association between enhanced early stimulus orienting (P2), impulsive action (response inhibition), and impaired signal-noise discriminability (A-prime).

Language: en

LA - en SN - 0940-1334 UR - http://dx.doi.org/10.1007/s00406-016-0734-1 ID - ref1 ER -