TY - JOUR PY - 2016// TI - The effects of partial sleep deprivation on energy balance: a systematic review and meta-analysis JO - European journal of clinical nutrition A1 - Al Khatib, H. K. A1 - Harding, S. V. A1 - Darzi, J. A1 - Pot, G. K. SP - 614 EP - 624 VL - 71 IS - 5 N2 - BACKGROUND/OBJECTIVES: It is unknown whether short sleep duration causatively contributes to weight gain. Studies investigating effects of partial sleep deprivation (PSD) on energy balance components report conflicting findings. Our objective was to conduct a systematic review and meta-analysis of human intervention studies assessing the effects of PSD on energy intake (EI) and energy expenditure (EE). SUBJECTS/METHODS: EMBASE, Medline, Cochrane CENTRAL, Web of Science and Scopus were searched. Differences in EI and total EE following PSD compared with a control condition were generated using the inverse variance method with random-effects models. Secondary outcomes included macronutrient distribution and resting metabolic rate. Heterogeneity was quantified with the I(2)-statistic.

RESULTS: Seventeen studies (n=496) were eligible for inclusion in the systematic review, and 11 studies (n=172) provided sufficient data to be included in meta-analyses. EI was significantly increased by 385 kcal (95% confidence interval: 252, 517; P<0.00001) following PSD compared with the control condition. We found no significant change in total EE or resting metabolic rate as a result of PSD. The observed increase in EI was accompanied by significantly higher fat and lower protein intakes, but no effect on carbohydrate intake.

CONCLUSIONS: The pooled effects of the studies with extractable data indicated that PSD resulted in increased EI with no effect on EE, leading to a net positive energy balance, which in the long term may contribute to weight gain.European Journal of Clinical Nutrition advance online publication, 2 November 2016; doi:10.1038/ejcn.2016.201.

Language: en

LA - en SN - 0954-3007 UR - http://dx.doi.org/10.1038/ejcn.2016.201 ID - ref1 ER -