TY  - JOUR
PY  - 2016//
TI  - History of lifetime suicide attempt in bipolar I disorder: its correlates and effect on illness course
JO  - International journal of psychiatry in clinical practice
A1  - Kattimani, Shivanand
A1  - Subramanian, Karthick
A1  - Sarkar, Siddharth
A1  - Rajkumar, Ravi Philip
A1  - Balasubramanian, Shanmuganathan
SP  - 118
EP  - 124
VL  - 21
IS  - 2
N2  - OBJECTIVES: To identify the prevalence and correlates of bipolar I patients with a lifetime history of suicide attempt. <br><br>MATERIALS AND METHODS: Bipolar I disorder was diagnosed in 150 patients as per DSM-IV-TR criteria. Their lifetime suicide risk was assessed using the Columbia Suicide Severity Rating Scale. NIMH retrospective Life Chart Methodology was used to chart the illness course. Medication Adherence Rating Scale (MARS) and Pittsburgh Sleep Quality Index (PSQI) were used to assess the recent adherence and subjective sleep quality, respectively. The suicide attempters were compared with non-attempters on individual variables. <br><br>RESULTS: Around 23% had a positive lifetime history of suicide attempt. They were predominantly female, had an index (first ever) episode of depression, spent more proportion of time being ill, especially in depressive or mixed episode phase. Comorbid substance use disorder along with suicidal attempts was seen only in males. Suicide attempters displayed poor medication adherence attitudes for medications taken during the past week and reported impaired sleep quality for the previous month. <br><br>CONCLUSIONS: A positive history of lifetime suicide attempt was significantly associated with a worse course of bipolar I disorder. Effective treatment of depressive episodes, addressing non-adherence, substance use and sleep problems can reduce the suicide risk in such patients. Retrospective design of the study and recall bias are some of the limitations.<p />  <p>Language: en</p>
LA  - en
SN  - 1365-1501
UR  - http://dx.doi.org/10.1080/13651501.2016.1250912
ID  - ref1
ER  -