TY  - JOUR
PY  - 2016//
TI  - Neuropsychological functioning of childhood trauma and post-traumatic stress disorder: a meta-analysis
JO  - Neuroscience and biobehavioral reviews
A1  - Malarbi, S.
A1  - Abu-Rayya, Hisham Motkal
A1  - Muscara, F.
A1  - Stargatt, R.
SP  - 68
EP  - 86
VL  - 72
IS  - 
N2  - This study reviewed evidence for cognitive impairments in trauma-exposed children with and without PTSD. Twenty-seven studies were eligible for meta-analysis, totalling 1,526 participants, including 412 trauma-exposed children (PTSD unknown), 300 children with PTSD (PTSD+), 323 children without PTSD (PTSD-), and 491 trauma-naive controls. Eligible studies mostly investigated familial-maltreatment trauma (k=22). Trauma-exposed children (PTSD unknown) performed more poorly overall than controls (d=-0.57). Cognitive deficits were seen in PTSD+ compared to controls, including a large effect size (ES) for general intelligence (d=-0.88), moderate ESs for language/verbal (d=-0.65), visuospatial (d=-0.53), information processing (d=-0.62), learning and memory (d=-0.67), and executive skills (d=-0.52). PTSD+ showed poorer general intelligence (d=-0.28) and visuospatial skills (d=-0.42) compared to PTSD-, whilst PTSD- showed poorer executive function (d=-0.23) and learning and memory (d=-0.61) compared to controls. In conclusion, trauma-exposed children showed cognitive deficits compared to controls, although greatest deficits were associated with PTSD diagnosis.<br><br>Copyright © 2016. Published by Elsevier Ltd.<p />  <p>Language: en</p>
LA  - en
SN  - 0149-7634
UR  - http://dx.doi.org/10.1016/j.neubiorev.2016.11.004
ID  - ref1
ER  -